3-CYANOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

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Reagent Code: #162823
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CAS Number 142253-46-1

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blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 210.27 g/mol
Formula C₁₁H₁₈N₂O₂
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) involving pyrrolidine-based structures. This compound features a pyrrolidine core with a cyanomethyl group at the 3-position and a tert-butoxycarbonyl (Boc) protecting group on the nitrogen. The cyano group enables selective reductions to aminomethyl functionalities, while the Boc group can be deprotected under mild acidic conditions to reveal the free pyrrolidine amine. These properties allow for versatile reactions in multi-step organic syntheses, making it valuable in drug discovery for central nervous system agents and enzyme inhibitors. Commonly employed in the preparation of proline analogs and peptidomimetics due to the stability and conformational properties of the pyrrolidine ring. Suitable for use in coupling reactions and catalytic transformations, supporting efficient route design in medicinal chemistry.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,030.00
inventory 1g
10-20 days ฿7,520.00
inventory 5g
10-20 days ฿28,410.00
inventory 10g
10-20 days ฿49,390.00

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3-CYANOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
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Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) involving pyrrolidine-based structures. This compound features a pyrrolidine core with a cyanomethyl group at the 3-position and a tert-butoxycarbonyl (Boc) protecting group on the nitrogen. The cyano group enables selective reductions to aminomethyl functionalities, while the Boc group can be deprotected under mild acidic conditions to reveal the free pyrrolid

Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) involving pyrrolidine-based structures. This compound features a pyrrolidine core with a cyanomethyl group at the 3-position and a tert-butoxycarbonyl (Boc) protecting group on the nitrogen. The cyano group enables selective reductions to aminomethyl functionalities, while the Boc group can be deprotected under mild acidic conditions to reveal the free pyrrolidine amine. These properties allow for versatile reactions in multi-step organic syntheses, making it valuable in drug discovery for central nervous system agents and enzyme inhibitors. Commonly employed in the preparation of proline analogs and peptidomimetics due to the stability and conformational properties of the pyrrolidine ring. Suitable for use in coupling reactions and catalytic transformations, supporting efficient route design in medicinal chemistry.

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