tert-Butyl((3R,4S)-4-fluoropyrrolidin-3-yl)carbamate
98%
Reagent
Code: #155656
CAS Number
1033718-91-0
blur_circular Chemical Specifications
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Molecular Information
Weight
204.24 g/mol
Formula
C₉H₁₇FN₂O₂
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Registry Numbers
MDL Number
MFCD24368650
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of antiviral and antidiabetic agents. Its fluorinated pyrrolidine structure enhances metabolic stability and bioavailability in drug candidates. Commonly employed in the preparation of protease inhibitors and DPP-4 inhibitors for type 2 diabetes treatment. The tert-butyl carbamate (Boc) group facilitates protection during peptide coupling and multi-step synthesis, allowing selective functionalization. Valued in medicinal chemistry for enabling stereoselective transformations and improving pharmacokinetic profiles of active compounds.
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