Used in pharmaceutical synthesis as a chiral building block for developing bioactive molecules, particularly in the preparation of fluorinated analogs of natural products and drug candidates. The difluoro and hydroxyl groups enhance metabolic stability and binding affinity, while the N-Boc protecting group on the pyrrolidine nitrogen allows for selective functionalization and easy deprotection to access the free amine. This makes it valuable in medicinal chemistry for optimizing pharmacokinetic properties. Commonly employed in the development of protease inhibitors, antiviral agents, and central nervous system agents due to its conformational rigidity and polarity profile.