tert-Butyl 3-amino-4-fluoropyrrolidine-1-carboxylate

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Reagent Code: #152005
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CAS Number 1260848-87-0

science Other reagents with same CAS 1260848-87-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 204.24 g/mol
Formula C₉H₁₇FN₂O₂
badge Registry Numbers
MDL Number MFCD14705158
thermostat Physical Properties
Boiling Point 266.1±40.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.13±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry, light-proof

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of biologically active compounds targeting central nervous system disorders and metabolic diseases. Its structure supports the construction of peptidomimetics and enzyme inhibitors, where the fluorinated pyrrolidine ring enhances metabolic stability and binding selectivity. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the constrained ring system and the presence of fluorine, which can improve bioavailability and membrane permeability. The tert-butyloxycarbonyl (Boc) protecting group allows for selective amine functionalization in multi-step syntheses, making it valuable in the preparation of complex drug candidates.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿3,390.00
inventory 250mg
10-20 days ฿5,780.00
inventory 1g
10-20 days ฿15,560.00

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tert-Butyl 3-amino-4-fluoropyrrolidine-1-carboxylate
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of biologically active compounds targeting central nervous system disorders and metabolic diseases. Its structure supports the construction of peptidomimetics and enzyme inhibitors, where the fluorinated pyrrolidine ring enhances metabolic stability and binding selectivity. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the constrained ring system and the pres

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of biologically active compounds targeting central nervous system disorders and metabolic diseases. Its structure supports the construction of peptidomimetics and enzyme inhibitors, where the fluorinated pyrrolidine ring enhances metabolic stability and binding selectivity. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the constrained ring system and the presence of fluorine, which can improve bioavailability and membrane permeability. The tert-butyloxycarbonyl (Boc) protecting group allows for selective amine functionalization in multi-step syntheses, making it valuable in the preparation of complex drug candidates.

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