tert-Butyl 4-amino-3,3-difluoropyrrolidine-1-carboxylate
≥95%
Reagent
Code: #148434
CAS Number
1408074-83-8
science Other reagents with same CAS 1408074-83-8
blur_circular Chemical Specifications
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Molecular Information
Weight
222.23 g/mol
Formula
C₉H₁₆F₂N₂O₂
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Registry Numbers
MDL Number
MFCD23105898
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Physical Properties
Boiling Point
261.7±40.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, protected from light, stored in inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and antidiabetic agents. Its structure supports the formation of bioactive molecules by providing a stable, fluorinated pyrrolidine scaffold that enhances metabolic stability and binding affinity. Commonly employed in medicinal chemistry for constructing peptidomimetics and CNS-active drugs due to favorable pharmacokinetic properties. Also utilized in the preparation of protease inhibitors and targeted therapies where selective fluorination improves drug performance.
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