N-Boc-2-pyrroleboronic acid
98%
Reagent
Code: #216640
Alias
1-Tert-butoxycarbonyl-2-pyrroleylboric acid
CAS Number
135884-31-0
blur_circular Chemical Specifications
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Molecular Information
Weight
211.02 g/mol
Formula
C₉H₁₄BNO₄
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Registry Numbers
MDL Number
MFCD01318939
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Physical Properties
Melting Point
93-98 °C (dec.)(lit.)
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Storage & Handling
Storage
-20°C
description Product Description
Widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the construction of complex pyrrole-containing frameworks found in pharmaceuticals and natural products. The Boc-protecting group stabilizes the pyrrole ring during reaction conditions and can be easily removed later in the synthesis. Its boronic acid functionality allows for efficient carbon-carbon bond formation with aryl or vinyl halides, making it valuable in drug discovery and the development of functional materials. Commonly employed in the synthesis of bioactive molecules, including kinase inhibitors and antitumor agents.
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