2-(Pyridin-2-yl)pyrimidine-5-carboxylic acid
≥95%
Reagent
Code: #86679
CAS Number
933988-22-8
science Other reagents with same CAS 933988-22-8
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Molecular Information
Weight
201.18 g/mol
Formula
C₁₀H₇N₃O₂
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Registry Numbers
MDL Number
MFCD09863210
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
2-(Pyridin-2-yl)pyrimidine-5-carboxylic acid is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of various biologically active compounds. Its structure is particularly valuable in the development of small molecule inhibitors, which are often targeted at specific enzymes or receptors involved in disease pathways. For instance, it has been explored in the design of kinase inhibitors, which are crucial in cancer therapy due to their role in regulating cell proliferation and survival. Additionally, this compound is employed in the creation of ligands for drug discovery, where its pyridine and pyrimidine moieties can interact with biological targets through hydrogen bonding and π-π stacking interactions. Its carboxylic acid group further allows for derivatization, enabling the attachment of various functional groups to enhance drug-like properties such as solubility, bioavailability, and target affinity. Overall, this chemical serves as a versatile building block in the development of potential therapeutic agents.
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