4-Amino-6-phenylpyrimidine is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of various pharmaceutical compounds. Its structure is often incorporated into molecules designed to target specific biological pathways, making it valuable in drug discovery and development. This compound is particularly significant in the creation of inhibitors for enzymes such as kinases, which play a critical role in cellular signaling and disease progression, including cancer and inflammatory disorders.

Additionally, it serves as a building block in the preparation of heterocyclic compounds, which are widely studied for their potential therapeutic applications. Its versatility allows researchers to modify its structure to enhance binding affinity, selectivity, and efficacy in drug candidates. Beyond pharmaceuticals, 4-amino-6-phenylpyrimidine is also explored in material science for the development of organic electronic materials due to its conjugated aromatic system, which can contribute to desirable electronic properties.