2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
95%
Reagent
Code: #42444
CAS Number
1352796-65-6
blur_circular Chemical Specifications
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Molecular Information
Weight
224.0398 g/mol
Formula
C₁₀H₁₄BFN₂O₂
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Registry Numbers
MDL Number
MFCD13182191
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Storage & Handling
Storage
2-8°C
description Product Description
This chemical is widely used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs). It plays a crucial role in Suzuki-Miyaura cross-coupling reactions, which are essential for creating complex organic molecules, including drug candidates. Its boronate ester group enables efficient and selective coupling with aryl or heteroaryl halides, making it valuable in medicinal chemistry for constructing pyrimidine-based compounds. These compounds are often explored for their potential in treating diseases such as cancer, viral infections, and inflammatory disorders. Additionally, it is utilized in agrochemical research for developing novel pesticides and herbicides. Its stability and reactivity make it a preferred choice in organic synthesis and industrial applications.
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