2-Methoxypyrimidine-5-boronic acid pinacol ester
98%
Reagent
Code: #208552
CAS Number
1052686-60-8
blur_circular Chemical Specifications
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Molecular Information
Weight
236.07 g/mol
Formula
C₁₁H₁₇BN₂O₃
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Registry Numbers
MDL Number
MFCD13182190
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Physical Properties
Boiling Point
354.3±34.0℃ at 760 mmHg
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Storage & Handling
Storage
2-8℃, inert gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronic ester group facilitates efficient and selective coupling with aryl or heteroaryl halides under mild conditions. Commonly employed in the development of bioactive molecules, including drug candidates containing pyrimidine scaffolds. The methoxy group enhances solubility and can influence electronic properties, improving reaction yields and selectivity. Stable and easy to handle, making it suitable for automated synthesis and library generation in medicinal chemistry.
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