2-Chloro-4-ethoxy-pyrimidine
97%
Reagent
Code: #164223
CAS Number
83774-09-8
blur_circular Chemical Specifications
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Molecular Information
Weight
158.586 g/mol
Formula
C₆H₇ClN₂O
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Registry Numbers
MDL Number
MFCD00234199
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Physical Properties
Melting Point
35 °C
Boiling Point
279 °C at 760 mmHg
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Storage & Handling
Density
1.235 g/cm3
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of agrochemicals, particularly herbicides and insecticides, due to its reactive chlorine and electron-deficient pyrimidine ring. Its ethoxy group enhances lipophilicity, improving membrane permeability in active ingredients. Also employed in pharmaceutical research for developing kinase inhibitors and other bioactive molecules. Commonly utilized in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig, to introduce aryl or amino substituents in drug discovery programs.
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