5-(2-Chloropyrimidin-4-yl)-2,4-difluorobenzonitrile
95%
Reagent
Code: #163801
CAS Number
1956307-41-7
blur_circular Chemical Specifications
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Molecular Information
Weight
251.62 g/mol
Formula
C₁₁H₄ClF₂N₃
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Registry Numbers
MDL Number
MFCD29059345
thermostat
Physical Properties
Boiling Point
412.9±45.0 °C(Predicted)
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Storage & Handling
Density
1.51±0.1 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for targeted cancer therapies. Its structure allows for selective binding to specific enzyme sites, making it valuable in creating compounds that modulate cellular signaling pathways. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the presence of halogen and nitrile functional groups, which enhance binding affinity and metabolic stability. Also utilized in the preparation of fluorinated analogs to improve pharmacokinetic properties in drug candidates.
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