6-Chloro-2-(pyridin-2-yl)pyrimidin-4-amine
97%
Reagent
Code: #160171
CAS Number
1014720-73-0
blur_circular Chemical Specifications
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Molecular Information
Weight
206.63 g/mol
Formula
C₉H₇ClN₄
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Registry Numbers
MDL Number
MFCD14706108
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Physical Properties
Boiling Point
296.4±22.0°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in pharmaceuticals targeting cancer pathways. It serves as a building block in the development of selective inhibitors for proteins involved in cell signaling, such as B-Raf and other tyrosine kinases. Its structure allows for effective binding to enzyme active sites, making it valuable in drug discovery programs focused on oncology. Also employed in the preparation of compounds with anti-inflammatory and antiviral properties. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to form hydrogen bonds and participate in π-π stacking interactions.
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