5-Bromo-2-(tert-butyldimethylsiloxy)pyrimidine
97%
Reagent
Code: #149583
CAS Number
121519-00-4
science Other reagents with same CAS 121519-00-4
blur_circular Chemical Specifications
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Molecular Information
Weight
289.24 g/mol
Formula
CH₁₇BrN₂OSi
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Registry Numbers
MDL Number
MFCD01318957
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Physical Properties
Boiling Point
72 °C(Press: 0.01 Torr)
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Storage & Handling
Density
1.232 g/cm3
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical research. Its structure allows for selective functionalization, making it valuable in the development of kinase inhibitors and other drug candidates. The silyl protecting group enhances stability during reactions, while the bromine moiety enables cross-coupling reactions such as Suzuki or Heck couplings. Commonly employed in the preparation of nucleoside analogs and heterocyclic systems found in antiviral and anticancer agents.
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