5-Bromo-2-(trifluoromethyl)pyrimidine
98%
Reagent
Code: #144523
CAS Number
799557-86-1
blur_circular Chemical Specifications
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Molecular Information
Weight
226.98 g/mol
Formula
C₅H₂BrF₃N₂
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Storage & Handling
Density
1.807±0.06 g/cm3(Predicted)
Storage
Room temperature, dry, sealed
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective functionalization, making it valuable in creating active pharmaceutical ingredients (APIs) with high potency. Commonly employed in cross-coupling reactions such as Suzuki and Negishi couplings to build complex drug-like molecules. Also utilized in agrochemical research for designing novel pesticides and herbicides due to its electron-withdrawing properties and stability. Its bromo and trifluoromethyl groups enhance binding affinity and metabolic stability in target compounds.
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