5-Bromo-2-(dimethylamino)pyrimidine
98%
Reagent
Code: #143495
Alias
2-(dimethylamino)-5-bromopyrimidine 5-bromo-N,N-dimethylpyrimidine-2-amine
CAS Number
38696-21-8
blur_circular Chemical Specifications
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Molecular Information
Weight
202.05 g/mol
Formula
C₆H₈BrN₃
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Registry Numbers
MDL Number
MFCD07368228
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in the preparation of active pharmaceutical ingredients (APIs) due to its reactive bromo and dimethylamino functional groups, which allow for further chemical modifications. Commonly employed in cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations to form carbon-nitrogen or carbon-carbon bonds. Also utilized in agrochemical research for designing novel compounds with biological activity. Its structure supports the creation of complex heterocyclic systems found in bioactive molecules.
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