4-(Trifluoromethyl)pyrimidine-5-carboxamide
95%
Reagent
Code: #130305
CAS Number
2639626-83-6
blur_circular Chemical Specifications
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Molecular Information
Weight
191.11 g/mol
Formula
C₆H₄F₃N₃O
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Registry Numbers
MDL Number
MFCD32173523
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Physical Properties
Boiling Point
292.3±40.0 °C(Predicted)
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Storage & Handling
Density
1.491±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals to improve metabolic stability and bioavailability in crop protection compounds. The trifluoromethyl group contributes to lipophilicity and resistance to oxidative degradation, making it valuable in optimizing drug candidates.
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