3-(2-(Trifluoromethyl)pyrimidin-5-yl)propanoic acid
97%
Reagent
Code: #129941
CAS Number
1216040-74-2
blur_circular Chemical Specifications
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Molecular Information
Weight
220.15 g/mol
Formula
C₈H₇F₃N₂O₂
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Registry Numbers
MDL Number
MFCD13705445
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Physical Properties
Boiling Point
253.0±40.0 °C(Predicted)
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Storage & Handling
Density
1.435±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals for designing herbicides and fungicides due to the stability and bioavailability imparted by the trifluoromethyl and pyrimidine groups. The carboxylic acid functionality allows for easy derivatization, making it valuable in medicinal chemistry for creating amide or ester prodrugs.
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