Tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate
98%
Reagent
Code: #242859
CAS Number
171559-74-3
blur_circular Chemical Specifications
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Molecular Information
Weight
254.24 g/mol
Formula
C₁₁H₁₄N₂O₅
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Registry Numbers
MDL Number
MFCD03342947
thermostat
Physical Properties
Boiling Point
399.4±42.0 °C(Predicted)
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Storage & Handling
Density
1.28±0.1 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of pyridone-based drugs. It serves as a building block for introducing the acetate functionality protected as a tert-butyl ester onto nitrogen-containing heterocycles. This compound is valuable in medicinal chemistry for constructing complex molecules with biological activity, especially in the preparation of kinase inhibitors and antimicrobial agents. Its nitro and ester groups allow further chemical transformations, enabling diverse derivatization for structure-activity relationship studies.
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