3-(Trimethylsilyl)pyridin-2(1H)-one
95%
Reagent
Code: #242722
CAS Number
17379-48-5
blur_circular Chemical Specifications
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Molecular Information
Weight
167.28 g/mol
Formula
C₈H₁₃NOSi
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Registry Numbers
MDL Number
MFCD22056190
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of nitrogen-containing heterocyclic compounds. Its silyl group enhances reactivity and selectivity in cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex molecules. Commonly employed in palladium-catalyzed reactions to form carbon-carbon bonds, especially in the preparation of pyridine-based drug candidates. Also serves as a protecting group reagent due to the stability and easy removal of the trimethylsilyl moiety under mild conditions.
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