3-(Trimethylsilyl)pyridin-2(1H)-one

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Reagent Code: #242722
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CAS Number 17379-48-5

science Other reagents with same CAS 17379-48-5

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Weight 167.28 g/mol
Formula C₈H₁₃NOSi
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MDL Number MFCD22056190
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of nitrogen-containing heterocyclic compounds. Its silyl group enhances reactivity and selectivity in cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex molecules. Commonly employed in palladium-catalyzed reactions to form carbon-carbon bonds, especially in the preparation of pyridine-based drug candidates. Also serves as a protecting group reagent due to the stability and easy removal of the trimethylsilyl moiety under mild conditions.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿11,210.00
inventory 250mg
10-20 days ฿19,040.00
inventory 1g
10-20 days ฿51,390.00

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3-(Trimethylsilyl)pyridin-2(1H)-one
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of nitrogen-containing heterocyclic compounds. Its silyl group enhances reactivity and selectivity in cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex molecules. Commonly employed in palladium-catalyzed reactions to form carbon-carbon bonds, especially in the preparation of pyridine-based drug candidates. Also serves as a protecting group reagent due to the stability and easy removal of the trimethylsilyl moiety under mild conditions.
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