Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-, (6R,12aR)-
≥98%
science Other reagents with same CAS 171596-36-4
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description Product Description
This compound serves as a crucial intermediate in the synthesis of phosphodiesterase type 5 (PDE5) inhibitors, notably analogs of Tadalafil, which are employed in treating erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. The specific (6R,12aR) stereochemistry enhances its utility in medicinal chemistry for developing bioactive molecules with vasodilatory and smooth muscle relaxant properties. Ongoing research explores its potential in broader therapeutic areas, including cardiovascular applications and enzyme inhibition studies, though it is primarily valued as a building block for pharmaceutical synthesis rather than a standalone therapeutic agent.
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| Test Parameter | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | 98-100 |
| NMR | Consistent with structure |
| Infrared Spectrum | Conforms to Structure |
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