Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-, (6R,12aR)-
99.5%
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description Product Description
This compound, a hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione derivative with a 1,3-benzodioxol-5-yl substituent and (6R,12aR) stereochemistry, is a specialty chemical used primarily in medicinal chemistry research. It belongs to a class of compounds structurally related to phosphodiesterase type 5 (PDE5) inhibitors like tadalafil. As such, it is investigated for its potential to inhibit PDE enzymes, leading to increased cGMP levels and applications in treating erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia. Its unique fused ring system and stereochemistry make it valuable for structure-activity relationship (SAR) studies in drug discovery, particularly for optimizing potency, selectivity, and pharmacokinetic properties in cardiovascular and urological therapeutics.
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| Test Parameter | Specification |
|---|---|
| Appearance | White to off-white to yellow solid |
| Purity | 99.45-100 |
| NMR | Conforms to Structure |
| Infrared Spectrum | Conforms to Structure |
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