5-((Trimethylsilyl)ethynyl)pyridin-2(1H)-one
95%
Reagent
Code: #48102
CAS Number
1064706-78-0
blur_circular Chemical Specifications
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Molecular Information
Weight
191.30 g/mol
Formula
C₁₀H₁₃NOSi
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Registry Numbers
MDL Number
MFCD30189381
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Storage & Handling
Storage
2-8°C, store under inert gas
description Product Description
Used in organic synthesis as a building block for more complex molecules, particularly in the development of pharmaceuticals and agrochemicals. It serves as a key intermediate in the preparation of heterocyclic compounds, which are often explored for their biological activity. The trimethylsilyl group acts as a protecting group for the ethynyl functionality, allowing selective reactions to occur at other sites of the molecule. This compound is also utilized in cross-coupling reactions, such as Sonogashira coupling, to create carbon-carbon bonds, which are essential in the synthesis of various organic materials and active pharmaceutical ingredients. Its pyridinone core is of interest in medicinal chemistry for designing drugs targeting enzymes or receptors.
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