2-Bromo-4-ethynylpyridine is primarily utilized in organic synthesis as a versatile building block for the creation of complex molecules. Its structure, featuring both a bromine atom and an ethynyl group on a pyridine ring, makes it valuable in cross-coupling reactions, such as Sonogashira coupling, which are essential in pharmaceutical and materials science research. The compound is often employed in the development of bioactive molecules, including potential drug candidates, due to its ability to introduce functional groups that enhance binding affinity or modify pharmacokinetic properties. Additionally, it serves as a precursor in the synthesis of heterocyclic compounds, which are widely used in agrochemicals, dyes, and advanced materials. Its reactivity also makes it a useful intermediate in the construction of molecular frameworks for organic electronics and coordination chemistry.