2-Chloro-5-methylpyridine 1-oxide is primarily used as an intermediate in the synthesis of various pharmaceutical compounds. It plays a significant role in the production of agrochemicals, particularly in the development of pesticides and herbicides. The compound is also utilized in organic synthesis to create complex molecules, including those with potential biological activity. Its unique structure makes it valuable in research and development for designing new drugs and chemical entities. Additionally, it is employed in the preparation of pyridine derivatives, which are essential in the manufacture of dyes, flavors, and fragrances.