4-(Trifluoromethyl)nicotinthioamide
science Other reagents with same CAS 158063-54-8
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and antiviral agents. Its structure supports binding to enzyme active sites, enhancing biological activity in drug candidates. Also employed in agrochemicals for improving metabolic stability and lipophilicity, which helps in better penetration and efficacy. Commonly utilized in research settings for structure-activity relationship (SAR) studies due to the electron-withdrawing trifluoromethyl group and thioamide functionality that influence reactivity and binding affinity.
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