4-(Trifluoromethyl)nicotinthioamide
Reagent
Code: #244815
CAS Number
158063-54-8
blur_circular Chemical Specifications
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Molecular Information
Weight
206.19 g/mol
Formula
C₇H₅F₃N₂S
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Registry Numbers
MDL Number
MFCD00205806
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and antiviral agents. Its structure supports binding to enzyme active sites, enhancing biological activity in drug candidates. Also employed in agrochemicals for improving metabolic stability and lipophilicity, which helps in better penetration and efficacy. Commonly utilized in research settings for structure-activity relationship (SAR) studies due to the electron-withdrawing trifluoromethyl group and thioamide functionality that influence reactivity and binding affinity.
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