4-(Trifluoromethyl)pyridine-2-sulfonicacid
Reagent
Code: #244454
CAS Number
2422999-74-2
science Other reagents with same CAS 2422999-74-2
blur_circular Chemical Specifications
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Molecular Information
Weight
227.16 g/mol
Formula
C₆H₄F₃NO₃S
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated drug candidates where enhanced metabolic stability and bioavailability are desired. Its sulfonic acid group allows for salt formation to improve solubility, while the trifluoromethyl group contributes to lipophilicity and electron-withdrawing effects, beneficial in tuning the pharmacokinetic properties of active compounds. Also employed in agrochemical research for designing novel pesticides and herbicides due to its ability to enhance compound stability and target specificity. Its structure serves as a building block in medicinal chemistry for constructing pyridine-based scaffolds in kinase inhibitors and other biologically active molecules.
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