5-(Trifluoromethyl)pyridine-2(1H)-thione
97%
Reagent
Code: #242971
CAS Number
76041-72-0
blur_circular Chemical Specifications
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Molecular Information
Weight
179.16 g/mol
Formula
C₆H₄F₃NS
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Registry Numbers
MDL Number
MFCD00128893
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Physical Properties
Melting Point
154-159 °C(lit.)
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Storage & Handling
Storage
Room temperature, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antifungal and antiviral agents. Its structure allows for easy functionalization, making it valuable in medicinal chemistry for building bioactive molecules. Also employed in agrochemicals to enhance the stability and efficacy of crop protection agents. The trifluoromethyl group contributes to increased lipophilicity and metabolic stability, which improves the pharmacokinetic properties of final active compounds. Additionally, it serves as a ligand or building block in catalysis and coordination chemistry for designing novel metal complexes.
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