5-(Trifluoromethyl)pyridine-2-sulfonyl chloride
98%
Reagent
Code: #242660
CAS Number
174485-72-4
blur_circular Chemical Specifications
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Molecular Information
Weight
245.61 g/mol
Formula
C₆H₃ClF₃NO₂S
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Registry Numbers
MDL Number
MFCD07369680
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Physical Properties
Melting Point
50-52 °C
Boiling Point
277.683°C at 760 mmHg
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Storage & Handling
Storage
-20°C, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of agrochemicals and bioactive molecules. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for introducing the 5-(trifluoromethyl)pyridine moiety into larger structures. This functionality is often exploited in the creation of herbicides and insecticides due to the enhanced metabolic stability and lipophilicity provided by the trifluoromethyl and pyridine groups. It is also employed in medicinal chemistry for constructing sulfonamide-based compounds with potential therapeutic activity.
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