1,2,3,6-TETRAHYDROPYRIDINE-4-YL-BORONIC ACID PINACOL ESTER
98%
Reagent
Code: #242509
CAS Number
375853-82-0
blur_circular Chemical Specifications
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Molecular Information
Weight
209.09 g/mol
Formula
C₁₁H₂₀BNO₂
thermostat
Physical Properties
Boiling Point
246℃
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Storage & Handling
Density
0.99g/cm3
Storage
-20℃, avoiding light
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its boronic ester functionality enables participation in Suzuki-Miyaura cross-coupling reactions, allowing for efficient carbon-carbon bond formation in complex molecule assembly. Commonly employed in medicinal chemistry for lead optimization due to its structural compatibility with heterocyclic systems and its ability to enhance binding selectivity in drug candidates. Also utilized in the preparation of pyridine-containing analogs for biological evaluation in drug discovery programs.
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