4-(Trifluoromethyl)nicotinamide
98%
Reagent
Code: #240716
CAS Number
158062-71-6
blur_circular Chemical Specifications
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Molecular Information
Weight
190.12 g/mol
Formula
C₇H₅F₃N₂O
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Registry Numbers
MDL Number
MFCD00126658
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Physical Properties
Melting Point
165°C
Boiling Point
292°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used in pharmaceutical research as a building block for synthesizing bioactive molecules, particularly in the development of drugs targeting central nervous system disorders. Its trifluoromethyl group enhances metabolic stability and membrane permeability, making it valuable in optimizing drug candidates. Also employed in agrochemicals to improve the efficacy and durability of crop protection agents. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to its electron-withdrawing properties and ability to influence binding affinity.
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