6-(Trifluoromethyl)pyridine-3-carboxaldehyde
97%
Reagent
Code: #240002
Alias
6-Trifluoromethyl nicolydehyde
CAS Number
386704-12-7
blur_circular Chemical Specifications
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Molecular Information
Weight
175.11 g/mol
Formula
C₇H₄F₃NO
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Registry Numbers
MDL Number
MFCD01862647
thermostat
Physical Properties
Melting Point
53 °C
Boiling Point
72 °C
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Storage & Handling
Storage
2~8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the production of nicotinic receptor modulators and agrochemicals. Its aldehyde functionality allows for easy derivatization, making it valuable in forming C–C and C–N bonds through condensation or reduction reactions. Commonly employed in the development of bioactive molecules due to the electron-withdrawing effect of the trifluoromethyl group, which enhances metabolic stability and lipophilicity in drug candidates. Also utilized in the preparation of ligands for catalysis and in the design of functional materials requiring specific electronic properties.
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