5-Nitro-2-(piperidin-4-yloxy)-pyridinehydrochloride
97%
Reagent
Code: #219592
CAS Number
1185309-69-6
blur_circular Chemical Specifications
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Molecular Information
Weight
259.689 g/mol
Formula
C₁₀H₁₄ClN₃O₃
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Registry Numbers
MDL Number
MFCD09607571
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of varenicline, a medication for smoking cessation. It enables the construction of the core structure of varenicline through selective functionalization and coupling reactions. Its nitro group can be reduced to an amine, which is further modified to form the diazabicyclic ring system present in the final drug. Due to its structural specificity, it plays a critical role in ensuring the correct pharmacological profile of the active pharmaceutical ingredient. Commonly employed in research and development settings for nicotine receptor modulators.
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