Widely used in cross-coupling reactions, especially in Suzuki-Miyaura coupling, to introduce functionalized pyridine moieties into organic molecules. Its boronate ester group readily reacts with aryl or heteroaryl halides in the presence of palladium catalysts, enabling the synthesis of complex nitrogen-containing compounds. Commonly employed in pharmaceutical and agrochemical research for constructing biaryl systems where a nitro-substituted pyridine is required. The nitro group can be further modified post-coupling, allowing additional derivatization such as reduction to an amine or participation in cyclization reactions. Its stability and reactivity make it a valuable building block in medicinal chemistry and materials science.