Used as a key intermediate in the synthesis of agrochemicals and pharmaceuticals, particularly in the development of herbicides and fungicides. Its trifluoromethyl group enhances lipophilicity and metabolic stability, making it valuable in designing bioactive molecules. Commonly employed in kinase inhibitor research due to its ability to improve binding affinity and selectivity. Also utilized in the preparation of pyrido[2,3-d]pyrimidine derivatives with potential antitumor and anti-inflammatory activities.