2-(Methylsulfonyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

98%

Reagent Code: #210469
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CAS Number 1052138-94-9

science Other reagents with same CAS 1052138-94-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 283.15 g/mol
Formula C₁₂H₁₈BNO₄S
badge Registry Numbers
MDL Number MFCD11878228
thermostat Physical Properties
Boiling Point 441.7±45.0 °C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to construct biaryl compounds. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in the development of active pharmaceutical ingredients (APIs). The methylsulfonyl moiety enhances electron-withdrawing properties, improving reaction selectivity and yield in drug discovery processes. Commonly applied in the preparation of kinase inhibitors and other bioactive molecules targeting inflammation, cancer, and central nervous system disorders. Its stability and reactivity profile make it suitable for late-stage functionalization in complex molecule assembly.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,220.00
inventory 250mg
10-20 days ฿3,110.00
inventory 1g
10-20 days ฿8,510.00
inventory 5g
10-20 days ฿42,480.00

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2-(Methylsulfonyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
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Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to construct biaryl compounds. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in the development of active pharmaceutical ingredients (APIs). The methylsulfonyl moiety enhances electron-withdrawing properties, improving reaction selectivity and yield in drug discovery processes. Commonly applied in the preparation of kinase inhibitors and other bioactive molecules targeting inflammation, cancer, and central nervous system disorders. Its stability and reactivity profile make it suitable for late-stage functionalization in complex molecule assembly.
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