Methyl 5-bromo-2-fluoronicotinate
98%
science Other reagents with same CAS 931105-37-2
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules targeting inflammatory and oncological diseases. Its structure allows for selective functionalization, making it valuable in constructing complex heterocyclic compounds in medicinal chemistry. Commonly employed in cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig aminations to introduce the nicotinate core into target molecules. Also utilized in agrochemical research for designing new pesticides and herbicides due to its fluorinated and brominated aromatic system, which enhances binding affinity and metabolic stability.
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