5-Iodo-3-methyl-2-(pivaloylamino)pyridine
95%
Reagent
Code: #200168
Alias
5-Iodo-3-methyl-2-(pivaloylamino)pyridine
CAS Number
677327-29-6
blur_circular Chemical Specifications
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Molecular Information
Weight
318.16 g/mol
Formula
C₁₁H₁₅IN₂O
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Registry Numbers
MDL Number
MFCD04218302
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Physical Properties
Melting Point
141-144℃
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Storage & Handling
Storage
Room temperature, light-proof, sealed
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective functionalization, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in cross-coupling reactions such as Suzuki or Heck reactions to introduce aryl or vinyl groups. Also utilized in the preparation of bioactive molecules targeting neurological disorders due to its ability to cross the blood-brain barrier. Preferred in research settings for its stability and reactivity profile in multi-step organic syntheses.
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