2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

≥95%

Reagent Code: #187341
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CAS Number 458532-86-0

science Other reagents with same CAS 458532-86-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 223.05 g/mol
Formula C₁₁H₁₅BFNO₂
badge Registry Numbers
MDL Number MFCD06798253
thermostat Physical Properties
Boiling Point 312.1±27.0 °C at 760 mmHg
inventory_2 Storage & Handling
Storage Room temperature, seal, dry, light-proof

description Product Description

Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing biaryl systems. It is particularly useful in the development of kinase inhibitors and other bioactive molecules where a fluoropyridine moiety enhances metabolic stability and binding affinity. The presence of the fluorine atom also allows for further functionalization or labeling, including in PET tracer development. Its stability and reactivity profile make it a preferred reagent in both academic research and industrial drug discovery processes.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿670.00
inventory 10g
10-20 days ฿4,720.00
inventory 25g
10-20 days ฿11,790.00
inventory 100g
10-20 days ฿40,910.00
inventory 5g
10-20 days ฿2,700.00

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2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
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Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing biaryl systems. It is particularly useful in the development of kinase inhibitors and other bioactive molecules where a fluoropyridine moiety enhances metabolic stability and binding affinity. The presence of the fluorine atom also allows for further functionalization or labeling, including in PET tracer development. Its stability and reactivity profile make it a preferred reagent in both academic research and industrial drug discovery processes.
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