5-ethynyl-2-(trifluoromethyl)pyridine
≥95%
Reagent
Code: #181991
CAS Number
1196155-24-4
science Other reagents with same CAS 1196155-24-4
blur_circular Chemical Specifications
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Molecular Information
Weight
171.12 g/mol
Formula
C₈H₄F₃N
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Registry Numbers
MDL Number
MFCD13189725
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective binding in biological systems, making it valuable in drug discovery. The ethynyl group enables coupling reactions, such as Sonogashira cross-coupling, facilitating the construction of complex molecules. Also employed in agrochemicals for creating novel pesticides with improved efficacy and environmental profiles. Its trifluoromethyl group enhances metabolic stability and lipophilicity, beneficial in optimizing drug candidates.
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