5-(Difluoromethyl)-2-ethynylpyridine
98%
Reagent
Code: #179757
CAS Number
1211526-75-8
blur_circular Chemical Specifications
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Molecular Information
Weight
153.13 g/mol
Formula
C₈H₅F₂N
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its ethynyl group allows for efficient coupling reactions, enabling the construction of complex drug molecules. The difluoromethyl moiety enhances metabolic stability and lipophilicity, improving bioavailability and target binding in active pharmaceutical ingredients. Commonly employed in medicinal chemistry for structure-activity relationship optimization.
Due to sensitivity to light and temperature, it should be stored and handled under controlled conditions to maintain purity and efficacy.
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