3-(Difluoromethyl)pyridin-2(1H)-one
95%
Reagent
Code: #179388
CAS Number
1806766-03-9
blur_circular Chemical Specifications
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Molecular Information
Weight
145.11 g/mol
Formula
C₆H₅F₂NO
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Registry Numbers
MDL Number
MFCD31699335
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Storage & Handling
Storage
2-8°C, sealed, dry, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective binding to enzyme active sites, enhancing drug efficacy. Also employed in agrochemicals to improve metabolic stability and bioavailability in crop protection agents. The difluoromethyl group contributes to increased lipophilicity and resistance to oxidative degradation, making it valuable in optimizing pharmacokinetic properties.
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