Used primarily as an intermediate in organic synthesis, especially in pharmaceuticals and agrochemicals. Its aldehyde and bromine functionalities allow for selective reactions such as cross-coupling, reduction, and condensation, making it valuable in constructing nitrogen-containing heterocyclic compounds. Commonly employed in the development of active pharmaceutical ingredients (APIs) where the nicotinaldehyde backbone is required. Also utilized in the synthesis of ligands for catalysts and in the preparation of functionalized pyridine derivatives for materials science applications.