Diethyl 4-iodopyridine-2,6-dicarboxylate
98%
Reagent
Code: #177648
CAS Number
120491-90-9
blur_circular Chemical Specifications
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Molecular Information
Weight
349.12 g/mol
Formula
C₁₁H₁₂INO₄
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Registry Numbers
MDL Number
MFCD11042539
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Physical Properties
Boiling Point
417.2±45.0 °C(Predicted)
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Storage & Handling
Density
1.635±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pyridine-based pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its iodine functionality allows for further cross-coupling reactions, such as Suzuki or Heck couplings, enabling the introduction of complex aromatic or heteroaromatic groups. The ester groups can be hydrolyzed or transformed into amides, making it valuable in medicinal chemistry for building structurally diverse compounds. Commonly employed in research settings for the preparation of functionalized pyridine derivatives with potential applications in oncology, inflammation, and central nervous system disorders.
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