2-(difluoromethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
98%
Reagent
Code: #177356
CAS Number
1220696-57-0
science Other reagents with same CAS 1220696-57-0
blur_circular Chemical Specifications
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Molecular Information
Weight
255.07 g/mol
Formula
C₁₂H₁₆BF₂NO₂
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Registry Numbers
MDL Number
MFCD18733449
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Storage & Handling
Storage
2-8°C
description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, this compound enables the formation of carbon-carbon bonds in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group readily reacts with aryl or heteroaryl halides in the presence of a palladium catalyst, making it valuable for constructing complex pyridine-based structures. It is especially useful in medicinal chemistry for modifying bioactive molecules and developing drug candidates with improved metabolic stability and binding affinity.
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