2-Chloro-4-iodo-3-(trimethylsilyl)pyridine
95%
science Other reagents with same CAS 1138444-01-5
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description Product Description
Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. The iodine and chloro substituents allow for selective functionalization, enabling the stepwise construction of complex molecules. The trimethylsilyl group acts as a protective or directing group and can be converted to other functional groups, such as aldehydes or alkynes, expanding its utility in heterocyclic chemistry. Commonly employed in the development of kinase inhibitors and other bioactive compounds.
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| Test Parameter | Specification |
|---|---|
| Appearance | Brown liquid |
| Purity (%) | 94.5-100 |
| Infrared Spectrum | Conforms to Structure |
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