4-Chloro-2-fluoronicotinaldehyde
95%
Reagent
Code: #160058
CAS Number
1232432-20-0
blur_circular Chemical Specifications
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Molecular Information
Weight
159.55 g/mol
Formula
C₆H₃ClFNO
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Registry Numbers
MDL Number
MFCD15143389
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Physical Properties
Boiling Point
235.0±35.0°C
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Storage & Handling
Storage
2-8°C, inert gas atmosphere
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) for central nervous system (CNS) drugs and kinase inhibitors. Its aldehyde and halogen functionalities allow for selective chemical modifications, making it valuable in constructing complex heterocyclic systems. Commonly employed in cross-coupling reactions and condensation processes to build fluorinated and chlorinated pyridine derivatives, which are prevalent in agrochemicals and medicinal chemistry. Its structural features enhance metabolic stability and bioavailability in drug candidates.
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