Used as a key intermediate in the synthesis of neonicotinoid insecticides, particularly in the production of clothianidin and related agrochemicals. Its structure allows for efficient coupling reactions with nitroguanidine derivatives, enabling the formation of biologically active compounds that act on insect nicotinic acetylcholine receptors. It is valued in crop protection formulations for systemic activity against sucking pests like aphids and whiteflies. Also explored in medicinal chemistry for potential neuroactive molecules due to its pyridine core and electrophilic ketone functionality.