5-Bromo-2-(trimethylsilyl)pyridine
95%
science Other reagents with same CAS 291312-74-8
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description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the production of kinase inhibitors and other bioactive molecules. Its bromo and trimethylsilyl groups allow for selective cross-coupling reactions, making it valuable in constructing complex organic frameworks via palladium-catalyzed reactions like Suzuki or Stille couplings. The trimethylsilyl group also functions as a temporary protecting group for functional groups in multi-step syntheses, as it can be easily removed under controlled conditions. Commonly employed in the development of agrochemicals and functional materials due to its stability and reactivity profile. Also utilized in research settings for the preparation of pyridine-based ligands and catalysts.
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