5-Bromo-2-(trimethylsilyl)pyridine

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Reagent Code: #153257
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CAS Number 291312-74-8

science Other reagents with same CAS 291312-74-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 230.19 g/mol
Formula C₈H₁₂BrNSi
badge Registry Numbers
MDL Number MFCD18839255
inventory_2 Storage & Handling
Storage 2-8°C, Inert Gas

description Product Description

Used as an intermediate in pharmaceutical synthesis, particularly in the production of kinase inhibitors and other bioactive molecules. Its bromo and trimethylsilyl groups allow for selective cross-coupling reactions, making it valuable in constructing complex organic frameworks via palladium-catalyzed reactions like Suzuki or Stille couplings. The trimethylsilyl group also functions as a temporary protecting group for functional groups in multi-step syntheses, as it can be easily removed under controlled conditions. Commonly employed in the development of agrochemicals and functional materials due to its stability and reactivity profile. Also utilized in research settings for the preparation of pyridine-based ligands and catalysts.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿900.00
inventory 250mg
10-20 days ฿1,860.00
inventory 1g
10-20 days ฿6,520.00
inventory 5g
10-20 days ฿28,300.00

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5-Bromo-2-(trimethylsilyl)pyridine
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Used as an intermediate in pharmaceutical synthesis, particularly in the production of kinase inhibitors and other bioactive molecules. Its bromo and trimethylsilyl groups allow for selective cross-coupling reactions, making it valuable in constructing complex organic frameworks via palladium-catalyzed reactions like Suzuki or Stille couplings. The trimethylsilyl group also functions as a temporary protecting group for functional groups in multi-step syntheses, as it can be easily removed under controlle

Used as an intermediate in pharmaceutical synthesis, particularly in the production of kinase inhibitors and other bioactive molecules. Its bromo and trimethylsilyl groups allow for selective cross-coupling reactions, making it valuable in constructing complex organic frameworks via palladium-catalyzed reactions like Suzuki or Stille couplings. The trimethylsilyl group also functions as a temporary protecting group for functional groups in multi-step syntheses, as it can be easily removed under controlled conditions. Commonly employed in the development of agrochemicals and functional materials due to its stability and reactivity profile. Also utilized in research settings for the preparation of pyridine-based ligands and catalysts.

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