6-Bromo-2-fluoropyridin-3-amine
97%
Reagent
Code: #151650
Alias
2-Fluoro-6-Bromo-3-aminopyridine
CAS Number
850220-97-2
science Other reagents with same CAS 850220-97-2
blur_circular Chemical Specifications
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Molecular Information
Weight
191.00 g/mol
Formula
C₅H₄BrFN₂
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Registry Numbers
MDL Number
MFCD13659314
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other biologically active compounds. Its structure, featuring bromo at position 6, fluoro at position 2, and amino at position 3 on the pyridine ring, allows for selective functionalization, making it valuable in medicinal chemistry for creating analogs with enhanced binding affinity. Commonly employed in the preparation of agrochemicals and drug candidates targeting inflammatory diseases and cancer. The presence of bromo, fluoro, and amino groups enables cross-coupling reactions (e.g., Suzuki or Buchwald-Hartwig couplings) and further derivatization, supporting its role in building complex heterocyclic systems.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Light brown to reddish brown solid |
| Purity (%) | 96.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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